Dexrazoxane for the treatment of chemotherapy-related side effects
نویسندگان
چکیده
منابع مشابه
Dexrazoxane for the treatment of chemotherapy-related side effects
For more than half a century, the different properties of dexrazoxane have captured the attention of scientists and clinicians. Presently, dexrazoxane is licensed in many parts of the world for two different indications: prevention of cardiotoxicity from anthracycline-based chemotherapy, and prevention of tissue injuries after extravasation of anthracyclines. This article reviews the historical...
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15 صفحه اولDexrazoxane (Totect): FDA review and approval for the treatment of accidental extravasation following intravenous anthracycline chemotherapy.
Management of anthracycline extravasation is problematic and most reports are anecdotal. On September 6, 2007, the U.S. Food and Drug Administration approved Totect 500 mg (dexrazoxane hydrochloride for injection) for the treatment of extravasation resulting from i.v. anthracycline chemotherapy. In two studies, a total of 57 evaluable patients experienced extravasation from peripheral vein or c...
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ژورنال
عنوان ژورنال: Cancer Management and Research
سال: 2014
ISSN: 1179-1322
DOI: 10.2147/cmar.s47238